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Article

Key signalling nodes in mammary gland development and cancer: Myc

1 Oct 2009

Abstract excerpt

Myc has been intensely studied since its discovery more than 25 years ago. Insight has been gained into Myc's function in normal physiology, where its role appears to be organ specific, and in cancer where many mechanisms contribute to aberrant Myc expression. Numerous signals and pathways converge on Myc, which in turn acts on a continuously growing number of identified targets, via transcriptional and...

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PMID: 19849814
DOI: 10.1186/bcr2406

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