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Article

Specialized Circuitry of Embryonic Stem Cells Promotes Genomic Integrity.

Critical reviews in oncogenesis - 1 Jan 2022

Tichy Elisia D

Abstract excerpt

Embryonic stem cells (ESCs) give rise to all cell types of the organism. Given the importance of these cells in this process, ESCs must employ robust mechanisms to protect genomic integrity or risk catastrophic propagation of mutations throughout the organism. Should such an event occur in daughter cells that will eventually contribute to the germline, the overall species health could dramatically decline. This...

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PMID: 36734869
DOI: 10.1615/CritRevOncog.2022042332

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