Article
Genotype specific age related changes in a transgenic rat model of Huntington's disease.
NeuroImage - 15 Oct 2011
Blockx Ines, Van Camp Nadja, Verhoye Marleen, Boisgard Raphael, Dubois Albertine, Jego Benoit, Jonckers Elisabeth, Raber Kerstin, Siquier Karine, Kuhnast Bertrand, Dollé Frédéric, Nguyen Huu Phuc, Von Hörsten Stephan, Tavitian Bertrand, Van der Linden Annemie
Abstract excerpt
We aimed to characterize the transgenic Huntington rat model with in vivo imaging and identify sensitive and reliable biomarkers associated with early and progressive disease status. In order to do so, we performed a multimodality (DTI and PET) longitudinal imaging study, during which the same Tg...
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