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Article

Transgenic rat model of Huntington's disease.

Human molecular genetics - 15 Mar 2003

von Hörsten Stephan, Schmitt Ina, Nguyen Huu Phuc, Holzmann Carsten, Schmidt Thorsten, Walther Thomas, Bader Michael, Pabst Reinhard, Kobbe Philipp, Krotova Jana, Stiller Detlef, Kask Ants, Vaarmann Annika, Rathke-Hartlieb Silvia, Schulz Jörg B, Grasshoff Ute, Bauer Ingrid, Vieira-Saecker Ana Maria Menezes, Paul Martin, Jones Lesley, Lindenberg Katrin S, Landwehrmeyer Bernhard, Bauer Andreas, Li Xiao-Jiang, Riess Olaf

Abstract excerpt

Huntington's disease (HD) is a late manifesting neurodegenerative disorder in humans caused by an expansion of a CAG trinucleotide repeat of more than 39 units in a gene of unknown function. Several mouse models have been reported which show rapid progression of a phenotype leading to death withi...

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PMID: 12620967
DOI: 10.1093/hmg/ddg075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12620967-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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