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Article

Progressive deterioration of reaction time performance and choreiform symptoms in a new Huntington's disease transgenic ratmodel.

Behavioural brain research - 30 Jun 2006

Cao Chunyan, Temel Yasin, Blokland Arjan, Ozen Hatice, Steinbusch Harry W M, Vlamings Rinske, Nguyen Huu Phuc, von Hörsten Stephan, Schmitz Christoph, Visser-Vandewalle Veerle

Abstract excerpt

We tested the hypothesis that a recently developed transgenic rat model of Huntington's disease (tgHD rats) showed an age-and genotype-dependent change in psychomotor performance and in the frequency of choreiform movements similar to HD patients. Wild type and tgHD (homozygotic and heterozygotic...

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Source

Identifiers

PMID: 16569446
DOI: 10.1016/j.bbr.2006.02.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-16569446-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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