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Article

CSF-1, IGF-1, and the control of postnatal growth and development

2 Jun 2010

Abstract excerpt

Abstract Review discusses macrophages as the major extrahepatic source of IGF-1, and how a surge of CSF-1 production contributes to the control of postnatal growth and organ maturation. Growth hormone controls somatic growth in mammals by regulating the production of IGF-1, which is predominantly made by the liver. The development of cells within the MPS is controlled by the lineage-specific growth factor M-CSF...

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Share to Growth Hormone and Insulin-like Growth Factors
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PMID: 20519640
DOI: 10.1189/jlb.0310158

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