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Article

The role of Vldlr in intraretinal angiogenesis in mice.

Investigative ophthalmology & visual science - 22 Aug 2011

Xia Chun-Hong, Lu Eric, Liu Haiquan, Du Xin, Beutler Bruce, Gong Xiaohua

Abstract excerpt

PURPOSE. To identify and characterize the r26 mouse line, which displays depigmented patches in the retina, and to determine the causative gene mutation and study the underlying mechanism. METHODS. Fundus examination, fluorescein angiography, histology, and immunostaining were used to determine the retinal phenotypes. Genome-wide linkage analysis, DNA sequencing, and an allelic test were used to identify the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21757581
DOI: 10.1167/iovs.10-7082
PMCID: PMC3176028

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