Article
Linkage and association of phospholipid transfer protein activity to LASS4.
Journal of lipid research - 1 Oct 2011
Rosenthal Elisabeth A, Ronald James, Rothstein Joseph, Rajagopalan Ramakrishnan, Ranchalis Jane, Wolfbauer G, Albers John J, Brunzell John D, Motulsky Arno G, Rieder Mark J, Nickerson Deborah A, Wijsman Ellen M, Jarvik Gail P
Abstract excerpt
Phospholipid transfer protein activity (PLTPa) is associated with insulin levels and has been implicated in atherosclerotic disease in both mice and humans. Variation at the PLTP structural locus on chromosome 20 explains some, but not all, heritable variation in PLTPa. In order to detect quantitative trait loci (QTLs) elsewhere in the genome that affect PLTPa, we performed both oligogenic and single QTL linkage...
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