Article
PLTP activity inversely correlates with CAAD: effects of PON1 enzyme activity and genetic variants on PLTP activity.
Journal of lipid research - 1 Jul 2015
Kim Daniel Seung, Burt Amber A, Ranchalis Jane E, Vuletic Simona, Vaisar Tomas, Li Wan-Fen, Rosenthal Elisabeth A, Dong Weijiang, Eintracht Jason F, Motulsky Arno G, Brunzell John D, Albers John J, Furlong Clement E, Jarvik Gail P
Abstract excerpt
Recent studies have failed to demonstrate a causal cardioprotective effect of HDL cholesterol levels, shifting focus to the functional aspects of HDL. Phospholipid transfer protein (PLTP) is an HDL-associated protein involved in reverse cholesterol transport. This study sought to determine the genetic and nongenetic predictors of plasma PLTP activity (PLTPa), and separately, to determine whether PLTPa predicted...
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