Article
Statistical mutation calling from sequenced overlapping DNA pools in TILLING experiments.
BMC bioinformatics - 14 Jul 2011
Missirian Victor, Comai Luca, Filkov Vladimir
Abstract excerpt
BACKGROUND: TILLING (Targeting induced local lesions IN genomes) is an efficient reverse genetics approach for detecting induced mutations in pools of individuals. Combined with the high-throughput of next-generation sequencing technologies, and the resolving power of overlapping pool design, TIL...
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