Article
HNF1B and JAZF1 genes, diabetes, and prostate cancer risk.
The Prostate - 1 May 2010
Stevens Victoria L, Ahn Jiyoung, Sun Juzhong, Jacobs Eric J, Moore Steven C, Patel Alpa V, Berndt Sonja I, Albanes Demetrius, Hayes Richard B
Abstract excerpt
BACKGROUND: Epidemiologic studies have shown that men with type II diabetes have a lower risk of prostate cancer than non-diabetic men. Recently, common variants in two genes, HNF1B and JAZF1, were found to be associated with both of these diseases. METHODS: We examined whether the relationship between HNF1B and JAZF1 variants and decreased prostate cancer risk may potentially be mediated through diabetes in two...
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