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Article

Inflammatory effects of blood leukocytes: association with vascular function in neuropeptide Y proline 7-genotyped type 2 diabetes patients.

Diabetes & vascular disease research - 1 Jul 2011

Kakko Tanja, Jaakkola Ulriikka, Raitakari Olli T, Kallio Jaana

Abstract excerpt

OBJECTIVE: We investigated the associations of inflammatory blood cell activation with vascular parameters in patients with type 2 diabetes to elucidate the possible mechanisms of accelerated atherosclerosis observed in subjects with the Leucine 7 to Proline 7 polymorphism (Leu7Pro) in the neuropeptide Y (NPY). METHODS: Our study included 31 Caucasian patients with type 2 diabetes; 12 of them had the Leu7Pro7...

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Identifiers

PMID: 21746772
DOI: 10.1177/1479164111415882

Genes

NPY

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Inflammatory effects of blood leukocytes: association with vascular function in neuropeptide Y proline 7-genotyped type 2 diabetes patients.PMID 21746772Read ↗

The Leu7Pro polymorphism of the signal peptide of neuropeptide Y (NPY) gene is associated with increased levels of inflammatory markers preceding vascular complications in patients with type 2 diabetes.Semantic proximity Read ↗

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