Article
The Leu7Pro polymorphism of the signal peptide of neuropeptide Y (NPY) gene is associated with increased levels of inflammatory markers preceding vascular complications in patients with type 2 diabetes.
Microvascular research - 1 Dec 2010
Jaakkola U, Kakko T, Seppälä H, Vainio-Jylhä E, Vahlberg T, Raitakari O T, Kallio J
Abstract excerpt
AIMS/HYPOTHESIS: The Leucine7 to Proline7 (Leu7Pro) polymorphism of the signal peptide of neuropeptide Y (NPY) increases risk for vascular complications in diabetes. Diabetes is associated with low-grade inflammation, which has an important role in the development of atherosclerosis. Currently, we followed diabetes patients to investigate, if the Pro7 allele is associated with the inflammation related to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.