Article
Leucine 7 to proline 7 polymorphism in the preproneuropeptide Y is associated with proteinuria, coronary heart disease, and glycemic control in type 1 diabetic patients.
Diabetes care - 1 Feb 2004
Pettersson-Fernholm Kim, Karvonen Matti K, Kallio Jaana, Forsblom Carol M, Koulu Markku, Pesonen Ullamari, Fagerudd Johan A, Groop Per-Henrik
Abstract excerpt
OBJECTIVE: Neuropeptide Y is a potent vasoconstrictor thought to enhance the development of atherosclerosis. The leucine 7 to proline 7 (Leu7Pro) polymorphism, located in the signal peptide part of the human preproneuropeptide Y, has been associated with serum lipid levels, intima-media thickness...
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