Article
Endothelial dysfunction is independent of inflammation and altered CCR7 T cell expression in patients with ankylosing spondylitis.
Clinical and experimental rheumatology - 1 Jan 2000
Sulicka Joanna, Surdacki Andrzej, Korkosz Mariusz, Mikołajczyk Tomasz, Strach Magdalena, Klimek Ewa, Guzik Tomasz, Grodzicki Tomasz
Abstract excerpt
OBJECTIVES: The accumulation of CCR7 (chemokine receptor 7) positive cells in the vessel wall may be involved in endothelial dysfunction and subsequent accelerated atherogenesis. CCR7 plays a crucial role in T cell and monocyte migration/homing and in priming of naive T lymphocytes in non-lymphoid tissues in chronic inflammatory diseases. Our objective was to investigate the endothelial function and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
