Article
Acute Effects of Linagliptin on Progenitor Cells, Monocyte Phenotypes, and Soluble Mediators in Type 2 Diabetes.
The Journal of clinical endocrinology and metabolism - 1 Feb 2016
Fadini Gian Paolo, Bonora Benedetta Maria, Cappellari Roberta, Menegazzo Lisa, Vedovato Monica, Iori Elisabetta, Marescotti Maria Cristina, Albiero Mattia, Avogaro Angelo
Abstract excerpt
CONTEXT: Circulating cells, including endothelial progenitor cells (EPCs) and monocyte subtypes, are involved in diabetic complications. Modulation of these cells may mediate additional benefits of glucose-lowering medications. OBJECTIVE: We assessed whether the dipeptidyl peptidase-4 (DPP-4) inhibitor linagliptin acutely modifies EPCs and monocyte subsets in patients with type 2 diabetes. DESIGN: This was a...
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