Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Roles of EXO1 and RPA1 Polymorphisms in Prognosis of Lung Cancer Patients Treated with Platinum-Based Chemotherapy.

Disease markers - 1 Jan 2022

He Jia, Wang Zhan, Wang Ying, Zou Ting, Li Xiang-Ping, Chen Juan

Abstract excerpt

Background: Lung cancer is one of the major causes of cancer-related mortality worldwide. DNA repair and damage response contribute to genomic instability that accompanies tumor progression. In this study, we focus on evaluating association between DNA repair polymorphisms of EXO1, RPA1, and prognosis in lung cancer patients whom received platinum-based chemotherapy. Methods: 593 lung cancer patients were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Repair Enzymes
Share to Exodeoxyribonucleases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Lung Neoplasms

Share to Platinum

Share to Polymorphism, Single Nucleotide

Share to Prognosis

Share to Replication Protein A

Source

Open in PubMed Open full text

Identifiers

PMID: 36277983
DOI: 10.1155/2022/3306189
PMCID: PMC9584701

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Roles of EXO1 and RPA1 Polymorphisms in Prognosis of Lung Cancer Patients Treated with Platinum-Based Chemotherapy.PMID 36277983Read ↗

Hypoxia pathway genetic variants predict survival of non-small-cell lung cancer patients receiving platinum-based chemotherapy.Semantic proximity Read ↗

Role of rs873601 Polymorphisms in Prognosis of Lung Cancer Patients Treated with Platinum-Based ChemotherapySemantic proximity Read ↗

Genetic variation in the DNA repair genes is predictive of outcome in lung cancer.Semantic proximity Read ↗

Potentially functional polymorphisms of EXO1 and risk of lung cancer in a Chinese population: A case-control analysis.Semantic proximity Read ↗

Single nucleotide polymorphisms of nucleotide excision repair pathway are significantly associated with outcomes of platinum-based chemotherapy in lung cancer.Semantic proximity Read ↗

Association between polymorphisms in XRCC1 gene and clinical outcomes of patients with lung cancer: a meta-analysis.Semantic proximity Read ↗

MicroRNA-related single-nucleotide polymorphism of XPO5 is strongly correlated with the prognosis and chemotherapy response in advanced non-small-cell lung cancer patients.Semantic proximity Read ↗

Potentially functional polymorphisms in DNA repair genes and non-small-cell lung cancer survival: a pathway-based analysis.Semantic proximity Read ↗

Genetic Polymorphisms and Platinum-based Chemotherapy Treatment Outcomes in Patients with Non-Small Cell Lung Cancer: A Genetic Epidemiology Study Based Meta-analysis.Semantic proximity Read ↗

Association of well-characterized lung cancer lncRNA polymorphisms with lung cancer susceptibility and platinum-based chemotherapy response.Semantic proximity Read ↗

Impact of XPO1 mutations on survival outcomes in metastatic non-small cell lung cancer (NSCLC).Semantic proximity Read ↗

Pharmacogenetics of the DNA repair pathways in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.