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Article

A point mutation in norA gene is responsible for quinolone resistance in Staphylococcus aureus.

Biochemical and biophysical research communications - 15 Nov 1990

Ohshita Y, Hiramatsu K, Yokota T

Abstract excerpt

Two norA genes associated with hydrophilic quinolone resistance in Staphylococcus aureus were identified on the two recombinant plasmids pMR8736 and pSA209; the former was derived from a quinolone-resistant strain MR8736, and the latter was derived from a fluoroquinolone-susceptible strain 209P. We compared functions of these two genes, norA8736 and norA209 respectively, by introducing them into E. coli MC1061....

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Source

Identifiers

PMID: 2173911
DOI: 10.1016/0006-291x(90)91549-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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A point mutation in norA gene is responsible for quinolone resistance in Staphylococcus aureus.PMID 2173911Read ↗

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Quinolone resistance mutations in the DNA gyrase gyrA and gyrB genes of Staphylococcus aureus.Semantic proximity Read ↗

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Mechanisms of quinolone resistance.Semantic proximity Read ↗

Characterization of NorR protein, a multifunctional regulator of norA expression in Staphylococcus aureus.Semantic proximity Read ↗

NorC, a new efflux pump regulated by MgrA of Staphylococcus aureus.Semantic proximity Read ↗

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Mechanism of quinolone resistance in Staphylococcus aureus.Semantic proximity Read ↗

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