Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparison of the nucleotide sequence and expression of norA genes and microbial susceptibility in 21 strains of Staphylococcus aureus.

Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2004

Noguchi Norihisa, Okada Hiroyuki, Narui Koji, Sasatsu Masanori

Abstract excerpt

The norA gene, which is located on the chromosome of Staphylococcus aureus, encodes the multidrug efflux protein with 12 transmembrane segments (TMS), and the overexpression of norA by the mutation of the transcriptional control region confers resistance to fluoroquinolones and antiseptics. In this study, the nucleotide sequence and transcriptional expression of norA genes were studied in six standard laboratory...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Anti-Infective Agents, Local

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Blotting, Northern

Share to Drug Resistance, Bacterial

Share to Fluoroquinolones

Share to Microbial Sensitivity Tests

Share to Multidrug Resistance-Associated Proteins

Share to Staphylococcus aureus

Source

Identifiers

PMID: 15383162
DOI: 10.1089/mdr.2004.10.197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparison of the nucleotide sequence and expression of norA genes and microbial susceptibility in 21 strains of Staphylococcus aureus.PMID 15383162Read ↗

Characterization of NorR protein, a multifunctional regulator of norA expression in Staphylococcus aureus.Semantic proximity Read ↗

Allele-based analysis revealed the critical functions of region 277-297 in the NorA efflux pump of Staphylococcus aureus.Semantic proximity Read ↗

Effect of promoter region mutations and mgrA overexpression on transcription of norA, which encodes a Staphylococcus aureus multidrug efflux transporter.Semantic proximity Read ↗

A mutation in the 5' untranslated region increases stability of norA mRNA, encoding a multidrug resistance transporter of Staphylococcus aureus.Semantic proximity Read ↗

Expression of norA, norB and norC efflux pump genes mediating fluoroquinolones resistance in MRSA isolatesSemantic proximity Read ↗

NorC, a new efflux pump regulated by MgrA of Staphylococcus aureus.Semantic proximity Read ↗

A point mutation in norA gene is responsible for quinolone resistance in Staphylococcus aureus.Semantic proximity Read ↗

Associations between resistance phenotype and gene expression in response to serial exposure to oxacillin and ciprofloxacin in Staphylococcus aureus.Semantic proximity Read ↗

Characterization of genetic changes associated with daptomycin nonsusceptibility in Staphylococcus aureus.Semantic proximity Read ↗

NorA plasmid resistance to fluoroquinolones: role of copy number and norA frameshift mutations.Semantic proximity Read ↗

Frequency and genetic characterization of multidrug-resistant mutants of Staphylococcus aureus after selection with individual antiseptics and fluoroquinolones.Semantic proximity Read ↗

Multidrug resistance in Staphylococcus aureus due to overexpression of a novel multidrug and toxin extrusion (MATE) transport protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.