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Article

Quinolone susceptibility of norA-disrupted Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 Oct 1997

Yamada H, Kurose-Hamada S, Fukuda Y, Mitsuyama J, Takahata M, Minami S, Watanabe Y, Narita H

Abstract excerpt

The MIC of norfloxacin for the norA-disrupted mutant termed RDN1, obtained from quinolone-susceptible Staphylococcus aureus RN4220, was eightfold lower than that for RN4220. The increase in susceptibility was related to an increase of drug accumulation by RDN1. These results indicate that NorA plays an important role in the susceptibility of quinolone-susceptible S. aureus to selected quinolones.

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Source

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Identifiers

PMID: 9333072
DOI: 10.1128/AAC.41.10.2308
PMCID: PMC164117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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