Article
FCεRI gene promoter polymorphisms and total IgE levels in susceptibility to atopic dermatitis in Korea.
Journal of Korean medical science - 1 Jul 2011
Park Kui Young, Park Mi Kyung, Kim Eun Joo, Lee Mi-Kyung, Seo Seong Jun
Abstract excerpt
IgE-dependent activation of mast cells and basophils through the high-affinity IgE receptor (FcεRI) is involved in the pathogenesis of allergen-induced immune responsiveness in atopic diseases like atopic dermatitis (AD). We sought to determine FcεRI gene polymorphisms are associated with AD in Korean patients, and analyzed the relevance of FcεRI gene polymorphisms and serum IgE levels. We conducted a...
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