Simultaneous detection of barrier- and immune-related gene variations in patients with atopic dermatitis by reverse blot hybridization assay.

doi:10.1111/ced.13367

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Article

Simultaneous detection of barrier- and immune-related gene variations in patients with atopic dermatitis by reverse blot hybridization assay.

Clinical and experimental dermatology - 1 Jun 2018

Yoon N Y, Wang H Y, Jun M, Jung M, Kim D H, Lee N R, Hong K-W, Seo S J, Choi E, Lee J, Lee H, Choi E H

Abstract excerpt

BACKGROUND: Hereditary factors are involved in the pathogenesis of atopic dermatitis (AD). However, AD-related gene variations are significantly different across ethnicities. AIM: To identify mutations and single-nucleotide polymorphisms (SNPs) in barrier- or immune-related genes from Korean patients with AD and compare the variations with those observed in nonatopic healthy controls (HCs), and to use novel...

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