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Article

Studies of myeloperoxidase gene expression at the cellular level by in situ hybridization.

Leukemia - 1 Dec 1990

Zaki S R, Austin G E, Swan D C, Hooper W C, Greer P W, Evatt B L, Chan W C

Abstract excerpt

Recent studies have demonstrated myeloperoxidase (MPO) gene expression during granulocytic differentiation. Since these studies have been done exclusively by Northern and dot blot analysis and frequently with mixed populations of cells, quantitative changes in gene expression for particular popul...

Topics

Adolescent
Adult
Aged
Autoradiography
Bone Marrow
Cell Differentiation
Cell Line
Female
Gene Expression
Hematopoiesis
Humans
Leukemia, Promyelocytic, Acute
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Nucleic Acid Hybridization

Peroxidase

Phenotype

RNA, Messenger

Source

Identifiers

PMID: 2173803

Genes

MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2173803-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Studies of myeloperoxidase gene expression at the cellular level by in situ hybridization.PMID 2173803Read ↗

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Expression of myeloperoxidase in acute myeloid leukemia blasts mirrors the distinct DNA methylation pattern involving the downregulation of DNA methyltransferase DNMT3B.Semantic proximity Read ↗

Granulocyte colony-stimulating factor induction of normal human bone marrow progenitors results in neutrophil-specific gene expression.Semantic proximity Read ↗

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Sequence comparison of putative regulatory DNA of the 5' flanking region of the myeloperoxidase gene in normal and leukemic bone marrow cells.Semantic proximity Read ↗

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An allelic association implicates myeloperoxidase in the etiology of acute promyelocytic leukemia.Semantic proximity Read ↗

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An Alu element in the myeloperoxidase promoter contains a composite SP1-thyroid hormone-retinoic acid response element.Semantic proximity Read ↗

Measuring Myeloperoxidase Activity in Biological SamplesSemantic proximity Read ↗

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