Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An Alu element in the myeloperoxidase promoter contains a composite SP1-thyroid hormone-retinoic acid response element.

The Journal of biological chemistry - 14 Jun 1996

Piedrafita F J, Molander R B, Vansant G, Orlova E A, Pfahl M, Reynolds W F

Abstract excerpt

An Alu element preceding the myeloperoxidase gene (MPO) contains four hexamer motifs related to the consensus recognition sequence for nuclear hormone receptors (AGGTCA), arranged as direct repeats with spacing of 2, 4, and 2 nucleotides (DR-2-4-2). Gel shift experiments and transient transfection assays demonstrate that these sequences include binding sites for retinoic acid and thyroid hormone receptors and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to Binding Sites

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Line

Share to DNA-Binding Proteins

Share to DNA Primers

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 8662930
DOI: 10.1074/jbc.271.24.14412

Genes

MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An Alu element in the myeloperoxidase promoter contains a composite SP1-thyroid hormone-retinoic acid response element.PMID 8662930Read ↗

An allelic association implicates myeloperoxidase in the etiology of acute promyelocytic leukemia.Semantic proximity Read ↗

Peroxisome proliferator-activated receptor gamma ligands regulate myeloperoxidase expression in macrophages by an estrogen-dependent mechanism involving the -463GA promoter polymorphism.Semantic proximity Read ↗

Cis-elements in the promoter region of the human myeloperoxidase (MPO) gene.Semantic proximity Read ↗

Sequence comparison of putative regulatory DNA of the 5' flanking region of the myeloperoxidase gene in normal and leukemic bone marrow cells.Semantic proximity Read ↗

Transcriptional regulation of the p67phox gene: role of AP-1 in concert with myeloid-specific transcription factors.Semantic proximity Read ↗

A myeloperoxidase polymorphism associated with reduced risk of lung cancer.Semantic proximity Read ↗

Genomic organization and promoter analysis of the mouse ADP-ribosylarginine hydrolase gene.Semantic proximity Read ↗

Myeloperoxidase promoter region polymorphism and lung cancer risk.Semantic proximity Read ↗

ALU Repeats in Promoters Are Position-Dependent Co-Response Elements (coRE) that Enhance or Repress Transcription by Dimeric and Monomeric Progesterone ReceptorsSemantic proximity Read ↗

Myelopoiesis in the zebrafish, Danio rerioSemantic proximity Read ↗

Analysis of multiple single nucleotide polymorphisms (SNPs) of myeloperoxidase (MPO) to screen for genetic markers associated with acute leukemia in Chinese Han population.Semantic proximity Read ↗

MyeloperoxidaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.