An Alu element in the myeloperoxidase promoter contains a composite SP1-thyroid hormone-retinoic acid response element.

doi:10.1074/jbc.271.24.14412

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Article

An Alu element in the myeloperoxidase promoter contains a composite SP1-thyroid hormone-retinoic acid response element.

The Journal of biological chemistry - 14 Jun 1996

Piedrafita F J, Molander R B, Vansant G, Orlova E A, Pfahl M, Reynolds W F

Abstract excerpt

An Alu element preceding the myeloperoxidase gene (MPO) contains four hexamer motifs related to the consensus recognition sequence for nuclear hormone receptors (AGGTCA), arranged as direct repeats with spacing of 2, 4, and 2 nucleotides (DR-2-4-2). Gel shift experiments and transient transfectio...

Topics

Alleles
Animals
Base Sequence
Binding Sites
Cell Line
Chloramphenicol O-Acetyltransferase
Chlorocebus aethiops
Consensus Sequence
DNA Primers
DNA-Binding Proteins
Homozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukemia, Myeloid, Acute

Molecular Sequence Data

Peroxidase

Polymerase Chain Reaction

Promoter Regions, Genetic

Receptors, Retinoic Acid

Source

Open in PubMed

Identifiers

PMID: 8662930
DOI: 10.1074/jbc.271.24.14412

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8662930-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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