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Article

Genetic, phenotypic and clinical features of acute lymphoblastic leukemias expressing myeloperoxidase mRNA detected by RT-PCR.

Leukemia - 1 Feb 1999

Serrano J, Román J, Jiménez A, Castillejo J A, Navarro J A, Sánchez J, García-Castellanos J M, Martín C, Maldonado J, Torres A

Abstract excerpt

Myeloperoxidase (MPO) is found in the azurophilic granules of normal myelocytic cells. Cytochemical staining for MPO activity is used clinically to distinguish myeloid from acute lymphoid leukemias (ALL). However, using a highly sensitive RT-PCR technique, it is possible to detect MPO mRNA in otherwise clear ALL. The significance of this finding remains poorly understood. We have extended our observations to a...

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Identifiers

PMID: 10025890
DOI: 10.1038/sj.leu.2401305

Genes

MPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic, phenotypic and clinical features of acute lymphoblastic leukemias expressing myeloperoxidase mRNA detected by RT-PCR.PMID 10025890Read ↗

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