Role of gag sequence in the biochemical properties and transforming activity of the avian sarcoma virus UR2-encoded gag-ros fusion protein.

doi:10.1128/JVI.64.12.5997-6009.1990

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Article

Role of gag sequence in the biochemical properties and transforming activity of the avian sarcoma virus UR2-encoded gag-ros fusion protein.

Journal of virology - 1 Dec 1990

Jong S M, Wang L H

Abstract excerpt

The transforming protein P68gag-ros of avian sarcoma virus UR2 is a transmembrane tyrosine protein kinase molecule with the gag portion protruding extracellularly. To investigate the role of the gag moiety in the biochemical properties and biological functions of the P68gag-ros fusion protein, retroviruses containing the ros coding sequence of UR2 were constructed and analyzed. The gag-free ros protein was...

Topics

Amino Acid Sequence
Animals
Avian Sarcoma Viruses
Base Sequence
Cell Membrane
Cell Transformation, Neoplastic
Cells, Cultured
Chick Embryo
Cloning, Molecular
Enhancer Elements, Genetic
Fusion Proteins, gag-onc

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Variation

Molecular Sequence Data

Mutagenesis, Site-Directed

Protein-Tyrosine Kinases

Proviruses

Restriction Mapping

Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 2173777
DOI: 10.1128/JVI.64.12.5997-6009.1990
PMCID: PMC248773

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2173777-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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