Article
Comprehensive testing of positionally cloned asthma genes in two populations.
American journal of respiratory and critical care medicine - 1 Nov 2007
Hersh Craig P, Raby Benjamin A, Soto-Quirós Manuel E, Murphy Amy J, Avila Lydiana, Lasky-Su Jessica, Sylvia Jody S, Klanderman Barbara J, Lange Christoph, Weiss Scott T, Celedón Juan C
Abstract excerpt
RATIONALE: Replication of gene-disease associations has become a requirement in complex trait genetics. OBJECTIVES: In studies of childhood asthma from two different ethnic groups, we attempted to replicate associations with five potential asthma susceptibility genes previously identified by positional cloning. METHODS: We analyzed two family-based samples ascertained through an asthmatic proband: 497...
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