Article
Protective association exhibited by the single nucleotide polymorphism (SNP) rs1052133 in the gene human 8-oxoguanine DNA glycosylase (hOGG1) with the risk of squamous cell carcinomas of the head & neck (SCCHN) among north Indians.
The Indian journal of medical research - 1 Jun 2011
Mitra Amit Kumar, Singh Sarvendra Vikram, Garg Vivek Kumar, Sharma Mandira, Chaturvedi Rashmi, Rath Srikanta Kumar
Abstract excerpt
BACKGROUND & OBJECTIVES: Imbalances in compactly regulated DNA repair pathways in the form of single nucleotide polymorphisms (SNPs) within vital DNA repair genes may result in insufficient DNA repair and increase in DNA breaks thus rendering the human system vulnerable to the debilitatory effects of grave diseases like cancers. The present study involves investigation of association of the non-synonymous SNP...
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