Article
Single nucleotide polymorphisms in the homologous recombination repair genes and breast cancer risk in Polish women.
The Tohoku journal of experimental medicine - 1 Jul 2011
Romanowicz-Makowska Hanna, Smolarz Beata, Zadrozny Marek, Westfal Boguslaw, Baszczynski Jakub, Polac Ireneusz, Sporny Stanislaw
Abstract excerpt
Genetic polymorphisms in homologous recombination repair genes that can lead to protein haploinsufficiency are generally associated with increased cancer risk. The aim of the present study was to evaluate associations between the risk of breast cancer and single nucleotide polymorphisms in the genes, encoding three key proteins of the homologous recombination repair: RAD51 (the human homologue of the E. coli RecA...
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