Article
[Relationship between RAD51-G135C/XRCC3-C241T polymorphisms and development of acute myeloid leukemia with recurrent chromosome translocation].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 May 2011
Yang Lin, Liu Liang, Mi Ying-chang, Li Jian-yong, Ma Xiao-tang, Ai Xiao-fei, Qin Tie-jun, Xu Ze-feng, Wang Jian-xiang, Xiao Zhi-jian
Abstract excerpt
OBJECTIVE: To investigate the relationship between DNA homologous recombination (HR) repair genes RAD51-G135C/XRCC3-C241T polymorphisms and development of acute myeloid leukemia (AML) with recurrent chromosome translocation. METHODS: Genomic DNA was extracted from bone marrow cells of 625 de novo AML patients and peripheral blood cells of 806 patient family members and 704 unrelated volunteers. Genotypes of...
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