Article
[Polymorphisms of RAD51(G135C) and XRCC3(C241T) genes and correlations thereof with prognosis and clinical outcomes of acute myeloid leukemia].
Zhonghua yi xue za zhi - 5 Feb 2008
Liu Liang, Yang Lin, Zhang Yue, Xu Ze-Feng, Yu Ming-Hua, Wang Jian-Xiang, Xiao Zhi-Jian
Abstract excerpt
OBJECTIVE: To investigate the impacts of RAD51G(135C) and XRCC3(C241T) genotypes on the response, adverse effects, and prognosis of acute myelocytic leukemia (AML). METHODS: RAD51(G135C), XRCC3(C241T), GSTT1, and GSTM1 genotypes were analyzed in 372 patients with AML, 226 males and 146 females, by PCR-RFLP or PCR. The Complete remission (CR) rate, adverse effects, overall survival (OS), and relapse-free survival...
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