Article
The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA.
Nucleic acids research - 1 Oct 2011
Leu Kevin, Obermayer Benedikt, Rajamani Sudha, Gerland Ulrich, Chen Irene A
Abstract excerpt
In the early 'RNA world' stage of life, RNA stored genetic information and catalyzed chemical reactions. However, the RNA world eventually gave rise to the DNA-RNA-protein world, and this transition included the 'genetic takeover' of information storage by DNA. We investigated evolutionary advantages for using DNA as the genetic material. The error rate of replication imposes a fundamental limit on the amount of...
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