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Error correction during DNA replication.

Physical review. E, Statistical, nonlinear, and soft matter physics - 1 Jul 2012

Sharma Ajeet K, Chowdhury Debashish

Abstract excerpt

DNA polymerase (DNAP) is a dual-purpose enzyme that plays two opposite roles in two different situations during DNA replication. It plays its a normal role as a polymerase catalyzing the elongation of a new DNA molecule by adding a monomer. However, it can switch to the role of an exonuclease and shorten the same DNA by cleavage of the last incorporated monomer from the nascent DNA. Just as misincorporated...

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PMID: 23005458
DOI: 10.1103/PhysRevE.86.011913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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