Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

magu is required for germline stem cell self-renewal through BMP signaling in the Drosophila testis.

Developmental biology - 1 Sept 2011

Zheng Qi, Wang Yiwen, Vargas Eric, DiNardo Stephen

Abstract excerpt

Understanding how stem cells are maintained in their microenvironment (the niche) is vital for their application in regenerative medicine. Studies of Drosophila male germline stem cells (GSCs) have served as a paradigm in niche-stem cell biology. It is known that the BMP and JAK-STAT pathways are necessary for the maintenance of GSCs in the testis (Kawase et al., 2004; Kiger et al., 2001; Schulz et al., 2004;...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Bone Morphogenetic Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila

Share to Embryo, Nonmammalian

Share to Extracellular Matrix Proteins

Share to Germ Cells

Share to Stem Cell Niche

Share to Testis

Source

Open in PubMed Open full text

Identifiers

PMID: 21723859
DOI: 10.1016/j.ydbio.2011.06.022
PMCID: PMC3431605

Genes

GSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

magu is required for germline stem cell self-renewal through BMP signaling in the Drosophila testis.PMID 21723859Read ↗

Traffic jam functions in a branched pathway from Notch activation to niche cell fate.Semantic proximity Read ↗

Hh signalling is essential for somatic stem cell maintenance in the Drosophila testis niche.Semantic proximity Read ↗

Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue.Semantic proximity Read ↗

Control of stem cell self-renewal in Drosophila spermatogenesis by JAK-STAT signaling.Semantic proximity Read ↗

Drosophila's contribution to stem cell researchSemantic proximity Read ↗

Pelota controls self-renewal of germline stem cells by repressing a Bam-independent differentiation pathway.Semantic proximity Read ↗

The RNA-binding protein Musashi is required intrinsically to maintain stem cell identity.Semantic proximity Read ↗

Niche-dependent modular regulation of the stem cell transcriptome separates cell identity and potentialSemantic proximity Read ↗

Intestinal epithelium-derived BMP controls stem cell self-renewal in Drosophila adult midgut.Semantic proximity Read ↗

Gene circuitry controlling a stem cell niche.Semantic proximity Read ↗

The niche-dependent feedback loop generates a BMP activity gradient to determine the germline stem cell fate.Semantic proximity Read ↗

The Drosophila BCL6 homolog Ken and Barbie promotes somatic stem cell self-renewal in the testis niche.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.