Article
Control of stem cell self-renewal in Drosophila spermatogenesis by JAK-STAT signaling.
Science (New York, N.Y.) - 21 Dec 2001
Tulina N, Matunis E
Abstract excerpt
Stem cells, which regenerate tissue by producing differentiating cells, also produce cells that renew the stem cell population. Signals from regulatory microenvironments (niches) are thought to cause stem cells to retain self-renewing potential. However, the molecular characterization of niches remains an important goal. In Drosophila testes, germ line and somatic stem cells attach to a cluster of support cells...
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