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Article

Common TNF-alpha, IL-1 beta, PAI-1, uPA, CD14 and TLR4 polymorphisms are not associated with disease severity or outcome from Gram negative sepsis.

BMC infectious diseases - 18 Sept 2007

Jessen Kristine Marie, Lindboe Sarah Bjerre, Petersen Anncatrine Luisa, Eugen-Olsen Jesper, Benfield Thomas

Abstract excerpt

BACKGROUND: Several studies have investigated single nucleotide polymorphisms (SNPs) in candidate genes associated with sepsis and septic shock with conflicting results. Only few studies have combined the analysis of multiple SNPs in the same population. METHODS: Clinical data and DNA from consecutive adult patients with culture proven Gram negative bacteremia admitted to a Danish hospital between 2000 and 2002....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 17877801
DOI: 10.1186/1471-2334-7-108
PMCID: PMC2034565

Genes

TNF
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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