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Article

Spindle assembly checkpoint regulates mitotic cell cycle progression during preimplantation embryo development.

PloS one - 1 Jan 2011

Wei Yanchang, Multi Saima, Yang Cai-Rong, Ma Junyu, Zhang Qing-Hua, Wang Zhen-Bo, Li Mo, Wei Liang, Ge Zhao-Jia, Zhang Chun-Hui, Ouyang Ying-Chun, Hou Yi, Schatten Heide, Sun Qing-Yuan

Abstract excerpt

Errors in chromosome segregation or distribution may result in aneuploid embryo formation, which causes implantation failure, spontaneous abortion, genetic diseases, or embryo death. Embryonic aneuploidy occurs when chromosome aberrations are present in gametes or early embryos. To date, it is still unclear whether the spindle assembly checkpoint (SAC) is required for the regulation of mitotic cell cycle...

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Identifiers

PMID: 21720555
DOI: 10.1371/journal.pone.0021557
PMCID: PMC3123354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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