Article
Cadm4 Restricts the Production of Cardiac Outflow Tract Progenitor Cells
1 May 2014
Abstract excerpt
Heart assembly requires input from two populations of progenitor cells, the first and second heart fields (FHF and SHF), that differentiate at distinct times and create different cardiac components. The cardiac outflow tract (OFT) is built through recruitment of late-differentiating, SHF-derived cardiomyocytes to the arterial pole of the heart. The mechanisms responsible for selection of an appropriate number of...
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