Article
Exploratory analysis of cell-based screening data for phenotype identification in drug-siRNA study.
International journal of computational biology and drug design - 1 Jan 2011
Tjhi William-Chandra, Lee Kee Khoon, Hung Terence, Tsang Ivor Wai-Hung, Ong Yew Soon, Bard Frederic, Racine Victor
Abstract excerpt
Most phenotype-identification methods in cell-based screening assume prior knowledge about expected phenotypes or involve intricate parameter-setting. They are useful for analysis targeting known phenotype properties; but need exists to explore, with minimum presumptions, the potentially-interesting phenotypes derivable from data. We present a method for this exploration, using clustering to eliminate...
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