Article
Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens.
BMC bioinformatics - 5 Jun 2008
Yin Zheng, Zhou Xiaobo, Bakal Chris, Li Fuhai, Sun Youxian, Perrimon Norbert, Wong Stephen T C
Abstract excerpt
BACKGROUND: The recent emergence of high-throughput automated image acquisition technologies has forever changed how cell biologists collect and analyze data. Historically, the interpretation of cellular phenotypes in different experimental conditions has been dependent upon the expert opinions of well-trained biologists. Such qualitative analysis is particularly effective in detecting subtle, but important,...
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