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Article

Automatic identification of subcellular phenotypes on human cell arrays.

Genome research - 1 Jun 2004

Conrad Christian, Erfle Holger, Warnat Patrick, Daigle Nathalie, Lörch Thomas, Ellenberg Jan, Pepperkok Rainer, Eils Roland

Abstract excerpt

Light microscopic analysis of cell morphology provides a high-content readout of cell function and protein localization. Cell arrays and microwell transfection assays on cultured cells have made cell phenotype analysis accessible to high-throughput experiments. Both the localization of each protein in the proteome and the effect of RNAi knock-down of individual genes on cell morphology can be assayed by manual...

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Identifiers

PMID: 15173118
DOI: 10.1101/gr.2383804
PMCID: PMC419791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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