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Article

Vaccine-induced HIV-specific CD8+ T cells utilize preferential HLA alleles and target-specific regions of HIV-1.

Journal of acquired immune deficiency syndromes (1999) - 1 Nov 2011

Friedrich David, Jalbert Emilie, Dinges Warren L, Sidney John, Sette Alessandro, Huang Yunda, McElrath M Juliana, Horton Helen

Abstract excerpt

Most T cell-based HIV-1 vaccine candidates induce responses of limited breadth for reasons that are unclear. We evaluated vaccine-induced T-cell responses in individuals receiving an HIV-1 recombinant adenoviral vaccine. Certain HLA alleles (B27, B57, B35, and B14) are preferentially utilized to...

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Identifiers

PMID: 21709567
DOI: 10.1097/QAI.0b013e318228f992
PMCID: PMC3196811

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21709567-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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