Generating and measuring effective vaccine-elicited HIV-specific CD8+ T cell responses

Abstract excerpt

PURPOSE OF REVIEW: There is growing consensus that eliciting CD8 + T cells in addition to antibodies may be required for an effective HIV vaccine for both prevention and cure. Here, we review key qualities of vaccine-elicited CD8 + T cells as well as major CD8 + T cell-based delivery platforms used in recent HIV vaccine clinical trials. RECENT FINDINGS: Much progress has been made in improving HIV immunogen...

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