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Article

Mutations in HCV non-structural genes do not contribute to resistance to nitazoxanide in replicon-containing cells.

Antiviral research - 1 Sept 2011

Yon Changsuek, Viswanathan Prasanth, Rossignol Jean-François, Korba Brent

Abstract excerpt

Nitazoxanide (NTZ) exhibits potent antiviral activity against hepatitis C virus (HCV) in cell culture. Previously, HCV replicon-containing cell lines resistant to NTZ were selected, but transfer the HCV NTZ-resistance phenotype was not observed following transfection of whole cell RNA. To further explore the nature of the resistance of HCV to NTZ, full length HCV replicon sequences were obtained from two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21703309
DOI: 10.1016/j.antiviral.2011.05.017
PMCID: PMC3159803

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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