The predictive value of IL28B gene polymorphism for spontaneous clearance in a single source outbreak cohort is limited in patients carrying the CCR5Δ32 mutation.

doi:10.1016/j.jhep.2011.03.011

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Article

The predictive value of IL28B gene polymorphism for spontaneous clearance in a single source outbreak cohort is limited in patients carrying the CCR5Δ32 mutation.

Journal of hepatology - 1 Dec 2011

Nattermann Jacob, Timm Jörg, Nischalke Hans Dieter, Olbrich Anne, Michalk Monika, Tillmann Hans L, Berg Thomas, Wedemeyer Heiner, Tenckhoff Hannelore, Wiese Manfred, Kullig Ulrike, Göbel Uwe, Capka Emanuela, Schiefke Ingolf, Güthof Wolfgang, Grüngreiff Kurt, König Ingrid, Roggendorf Michael, Sauerbruch Tilman, Spengler Ulrich

Abstract excerpt

BACKGROUND & AIMS: The CCR5Δ32 mutation has been suspected to adversely affect outcomes of HCV infection, although reports have remained controversial. Here, we investigated the relative genetic contributions of the CCR5Δ32 deletion and the IL28B rs12979860 polymorphisms to spontaneous clearance of hepatitis C in a single-source outbreak. METHODS: We retrieved 396 Caucasian women (119 women with spontaneous HCV...

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PMID: 21703201
DOI: 10.1016/j.jhep.2011.03.011

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CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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