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Article

Transforming growth factor-β-induced protein (TGFBI) suppresses mesothelioma progression through the Akt/mTOR pathway.

International journal of oncology - 1 Oct 2011

Wen Gengyun, Hong Mei, Li Bingyan, Liao Wupeng, Cheng Simon K, Hu Burong, Calaf Gloria M, Lu Ping, Partridge Michael A, Tong Jian, Hei Tom K

Abstract excerpt

As an uncommon cancer, mesothelioma is very hard to treat with a low average survival rate owing to its usual late detection and being highly invasive. The link between asbestos exposure and the development of mesothelioma in humans is unequivocal. TGFBI, a secreted protein that is induced by transforming growth factor-β in various human cell types, has been shown to be associated with tumorigenesis in various...

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Source

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Identifiers

PMID: 21701776
DOI: 10.3892/ijo.2011.1097
PMCID: PMC4090925

Genes

TGFBI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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