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Molecular biology of malignant mesothelioma

28 Feb 2008

Abstract excerpt

Human malignancies develop via a multi-step that involves the accumulation of several key gene alterations with associated genetic and epigenetic events. Although malignant mesothelioma (MM) has been demonstrated to be clearly correlated with asbestos exposure, it remains poorly understood how asbestos fibers confer key gene alterations and induce cellular transformation in normal mesothelial cells, which results...

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PMID: 19568883
DOI: 10.1007/s12199-007-0015-8

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