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Article

Genomic abnormalities and signal transduction dysregulation in malignant mesothelioma cells.

Cancer science - 1 Jan 2010

Sekido Yoshitaka

Abstract excerpt

Malignant mesothelioma (MM) is a tumor with poor prognosis associated with asbestos exposure. While it remains to be clarified how asbestos fibers confer genetic/epigenetic alterations and induce cellular transformation in normal mesothelial cells, the understanding of key molecular mechanisms of MM cell development, proliferation, and invasion has progressed. MM shows frequent genetic inactivation of tumor...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19793348
DOI: 10.1111/j.1349-7006.2009.01336.x
PMCID: PMC11159396

Genes

EGFR
MET

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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