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Article

The role of TGFBI in mesothelioma and breast cancer: association with tumor suppression

13 Jun 2012

Abstract excerpt

BACKGROUND: Transforming growth factor β induced (TGFBI) product, an extracellular matrix (ECM) protein, has been implicated as a putative tumor suppressor in recent studies. Our previous findings revealed that expression of TGFBI gene is down-regulated in a variety of cancer cell lines and clinical tissue samples. In this study, ectopic expression of TGFBI was used to ascertain its role as a tumor suppressor and...

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PMID: 22695319
DOI: 10.1186/1471-2407-12-239

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