Article
Roadblock repression of transcription by Bacillus subtilis CodY.
Journal of molecular biology - 26 Aug 2011
Belitsky Boris R, Sonenshein Abraham L
Abstract excerpt
CodY is a global transcriptional regulator that is known to control, directly or indirectly, expression of more than 100 genes and operons in Bacillus subtilis. Using a combination of mutational analysis and DNase I footprinting experiments, we identified two high-affinity CodY-binding sites that contribute to repression of the ybgE gene and appear to act independently. One of these sites, located 80 bp...
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